Publications

2023

  1. Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Keswani SG, Li S, Bouchard LS, Butte MJ. Systemic enhancement of antitumour immunity by peritumourally implanted immunomodulatory macroporous scaffolds. Nat Biomed Eng. 2023 Jan;7(1):56-71. doi: 10.1038/s41551-022-00977-0. Epub 2022 Dec 22. PMID: 36550304; PMCID: PMC9940651.
    • This paper was chosen for the cover image.
  2. Du H, Bartleson JM, Butenko S, Alonso V, Liu WF, Winer DA, Butte MJ. Tuning immunity through tissue mechanotransduction. Nat Rev Immunol. 2023 Mar;23(3):174-188. doi: 10.1038/s41577-022-00761-w. Epub 2022 Aug 16. PMID: 35974148; PMCID: PMC9379893.
    • This paper was chosen for the cover image.

2022

  1. Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, Denny CT, Sul JH, Zaitlen N, Arboleda VA, Halperin E, Sankararaman S, Butte MJ; UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group; Lajonchere C, Geschwind DH, Pasaniuc B. Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Med. 2022 Nov 16;14(1):128. doi: 10.1186/s13073-022-01128-5. Erratum for: Genome Med. 2022 Sep 9;14(1):104. PMID: 36384576; PMCID: PMC9670414.
  2. Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, Çelik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, Gómez-Carballa A, Rivero-Calle I, Martinón-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultström M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A; COVID-19 Host Genetics Initiative; DeCOI Host Genetics Group; GEN-COVID Multicenter Study (Italy); Mount Sinai Clinical Intelligence Center; GEN-COVID consortium (Spain); GenOMICC Consortium; Japan COVID-19 Task Force; Regeneron Genetics Center; Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. Exome- wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 Nov 3;18(11):e1010367. doi: 10.1371/journal.pgen.1010367. PMID: 36327219; PMCID: PMC9632827.
  3. Matuozzo D, Talouarn E, Marchal A, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Zhang P, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Tayoun AA, Aiuti A, Darazam IA, Allende LM, Alonso- Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino- Neto A, Covill LE, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoğlu N, Karbuz A, Keles S, Kyheng C, Leon- Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Akcan OM, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, Pérez de Diego R, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Baris- Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, von Bernuth H, Lermine A, Vidaud M, Boland A, Deleuze JF, Nussbaum R, Kahn-Kirby A, Mentre F, Tubiana S, Gorochov G, Tubach F, Hausfater P; COVID Human Genetic Effort; COVIDeF Study Group; French COVID Cohort Study Group; CoV-Contact Cohort; COVID-STORM Clinicians; COVID Clinicians; Orchestra Working Group; Amsterdam UMC Covid-19 Biobank; NIAID-USUHS COVID Study Group; Meyts I, Zhang SY, Puel A, Notarangelo LD, Boisson-Dupuis S, Su HC, Boisson B, Jouanguy E, Casanova JL, Zhang Q, Abel L, Cobat A. Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. medRxiv [Preprint]. 2022 Oct 25:2022.10.22.22281221. doi: 10.1101/2022.10.22.22281221. PMID: 36324795; PMCID: PMC9628204.
  4. Butte MJ, Stein JV, Delon J. Editorial: The cytoskeleton in T cell migration and activation. Front Immunol. 2022 Oct 14;13:1057533. doi: 10.3389/fimmu.2022.1057533. PMID: 36311712; PMCID: PMC9614363.
  5. Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, Denny CT, Sul JH, Zaitlen N, Arboleda VA, Halperin E, Sankararaman S, Butte MJ; UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group; Lajonchere C, Geschwind DH, Pasaniuc B. Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Med. 2022 Sep 9;14(1):104. doi: 10.1186/s13073-022-01106-x. Erratum in: Genome Med. 2022 Nov 16;14(1):128. PMID: 36085083; PMCID: PMC9461263.
  6. Csomos K, Ujhazi B, Blazso P, Herrera JL, Tipton CM, Kawai T, Gordon S, Ellison M, Wu K, Stowell M, Haynes L, Cruz R, Zakota B, Nguyen J, Altrich M, Geier CB, Sharapova S, Dasso JF, Leiding JW, Smith G, Al-Herz W, de Barros Dorna M, Fadugba O, Fronkova E, Kanderova V, Svaton M, Henrickson SE, Hernandez JD, Kuijpers T, Kandilarova SM, Naumova E, Milota T, Sediva A, Moshous D, Neven B, Saco T, Sargur R, Savic S, Sleasman J, Sunkersett G, Ward BR, Komatsu M, Pittaluga S, Kumanovics A, Butte MJ, Cancro MP, Pillai S, Meffre E, Notarangelo LD, Walter JE. Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells. Nat Immunol. 2022 Aug;23(8):1256-1272. doi: 10.1038/s41590-022-01271-6. Epub 2022 Jul 28. PMID: 35902638; PMCID: PMC9355881.
  7. Short WD, Steen E, Kaul A, Wang X, Olutoye OO 2nd, Vangapandu HV, Templeman N, Blum AJ, Moles CM, Narmoneva DA, Crombleholme TM, Butte MJ, Bollyky PL, Keswani SG, Balaji S. IL-10 promotes endothelial progenitor cell infiltration and wound healing via STAT3. FASEB J. 2022 Jul;36(7):e22298. doi: 10.1096/fj.201901024RR. PMID: 35670763; PMCID: PMC9796147.
  8. Butte MJ, Kobayashi RH. An Updated Survey of SCID Outcomes Without Preconditioning Chemotherapy. J Allergy Clin Immunol Pract. 2022 Apr;10(4):1084-1085. doi: 10.1016/j.jaip.2022.01.024. PMID: 35397808.
  9. Zhang X, Hasani-Sadrabadi MM, Zarubova J, Dashtimighadam E, Haghniaz R, Khademhosseini A, Butte MJ, Moshaverinia A, Aghaloo T, Li S. Immunomodulatory Microneedle Patch for Periodontal Tissue Regeneration. Matter. 2022 Feb 2;5(2):666-682. doi: 10.1016/j.matt.2021.11.017. Epub 2021 Dec 8. PMID: 35340559; PMCID: PMC8942382.
  10. Zhang X, Kim TH, Thauland TJ, Li H, Majedi FS, Ly C, Gu Z, Butte MJ, Rowat AC, Li S. Corrigendum to "Unraveling the mechanobiology of immune cells" [Curr Opin Biotechnol 66 (2020) 236-245]. Curr Opin Biotechnol. 2022 Feb;73:387-388. doi: 10.1016/j.copbio.2021.10.019. Epub 2021 Dec 9. Erratum for: Curr Opin Biotechnol. 2020 Dec;66:236-245. PMID: 34895976; PMCID: PMC8655620.

2021

  1. Abraham RS, Butte MJ. The New “Wholly Trinity” In The Diagnosis and Management Of Inborn Errors Of Immunity. JACI in Practice. 9 (2), 613-625, 2021.
  2. Chang TS, Ding Y, Freund MK, Johnson R, Schwarz T, Yabu JM, Hazlett C, Chiang JN, Wulf A, Geschwind DH, Butte MJ (co-senior author), Pasaniuc B. Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors. iScience. 24 (3), 102188, 2021.
  3. Bloom JS, …, Butte MJ, …, Arboleda VA. Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples. Nature Biomedical Engineering. 2021, 5, 657–665.
  4. Khan HA and Butte MJ. Expanding the Potential Genes of Inborn Errors of Immunity through Protein Interactions. BMC Genomics. 2021 Oct 15;22(1):745. PMID: 34654376.
  5. Sancho-Shimizu V, Brodin P, Cobat A, Biggs CM, Toubiana J, Lucas CL, Henrickson SE, Belot A; MIS-C@CHGE, Tangye SG, Milner JD, Levin M, Abel L, Bogunovic D, Casanova JL, Zhang SY. SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?. J Exp Med. 2021 Jun 7;218(6):e20210446. doi: 10.1084/jem.20210446. PMID: 33904890
  6. Asano T, … COVID Human Genetic Effort… Casanova JL. X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19. Science Immunol. 2021 Aug 19;6(62):eabl4348. PMID: 34413140
  7. Bastard P, … COVID Human Genetic Effort… Casanova JL. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science Immunol. 2021 Aug 19. PMID: 34413139
  8. Salter CG, …, Butte MJ, … Baple EL. Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain. 2021 Aug 20. PMID: 34415310.
  9. Kohn LA, Horowitz H, Butte MJ, Devaskar UP. Prevention of Cytomegalovirus (CMV) Transmission via Maternal Breast Milk to an Infant with Severe Combined Immunodeficiency (SCID) using Kimie: New Compact Breast Milk Pasteurizer. J Pediatric Neonatal 3.2 (2021): 1-4.
  10. Zhang X, Hasani-Sadrabadi MM, Zarubova J, Dashtimighadam E, Haghniaz R, Khademhosseini A, Butte MJ, Moshaverinia A, Aghaloo T, Li S. Immunomodulatory microneedle patch for periodontal tissue regeneration. Matter, 2021, in press.

2020

  1. Tsai MS, Wonnaparhoun A, Garcia-Lloret MI, Butte MJ. Chronic Rhinosinusitis in Pediatric Immunodeficiency. In press, Current Treatment Options in Allergy, 2020. 7:219–232. Doi: 10.1007/s40521-019-00230-1.
  2. Béziat V, …, Kohn LA, …, Butte MJ, …Casanova JL, Puel A. Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. The Journal of Experimental Medicine. 2020 Jun 1;217(6). pii: e20191804. doi: 10.1084/jem.20191804.
  3. Steen EH, Wang X, Balaji S, Butte MJ, Bollyky PL, Keswani SG. The Role of the Anti-Inflammatory Cytokine Interleukin-10 in Tissue Fibrosis. Adv Wound Care. 2020 Apr 1;9(4):184-198. doi: 10.1089/wound.2019.1032.
  4. Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Li S, Bouchard L-S, Butte MJ. T-cell activation is modulated by the 3D mechanical microenvironment. Biomaterials. Volume 252, September 2020, 120058. doi: 10.1016/j.biomaterials.2020.120058
  5. A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection. Cell. 181, June 11 2020. doi: 10.1016/j.cell.2020.05.016
  6. Lin CH, Kuehn HS, Lee CM, DeRavin SS, Malech HL, Keyes TJ, Jager A, Davis KL, Rosenzweig SD, Butte MJ. Progressive B-cell loss in revertant X-SCID. Journal of Clinical Immunology. 2020 Jul 17. doi: 10.1007/s10875-020-00825-3. PMCID: PMC7508923.
  7. Goodwin M, Lee E, Lakshmanan U, Shipp S, Froessl L, Barzaghi F, Passerini L, Narula M, Sheikali A, Lee CM, Bao G, Bauer CS, Miller HK, Garcia-Lloret M, Butte MJ, Bertaina A, Shah A, Pavel-Dinu M, Hendel A, Porteus M, Roncarolo MG, Bacchetta R. CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells. Science Advances. 2020 May 6;6(19):eaaz0571. doi: 10.1126/sciadv.aaz0571
  8. Mohammad Mahdi Hasani‐Sadrabadi MM, Majedi FS, Miller ML, Thauland TJ, Bouchard L-S, Li S, Butte MJ. Augmenting T-cell responses to tumors by in situ nanomanufacturing. Materials Horizons, 2020 Nov 1;7(11):3028-3033. doi: 10.1039/D0MH00755B. PMID: 33343906, PMCID: PMC7748250
  9. Izadi N, Thauland TJ, Butte MJ, Snow A, Church JA. CADINS in an adult with chronic sinusitis and atopic disease. Journal of Clinical Immunology, Oct 2020. https://doi.org/10.1007/s10875-020-00893-5.
  10. Dorsey M, …, Butte MJ, …, Heimall J. Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers. Journal of Clinical Immunology, 2020, 11, 2852. PMID: 33006109. PMCID pending
  11. Merselis LC, Jiang S, Undiagnosed Diseases Network, Nelson S, Lee H, Prabaker KK, Baker JL, Munson GP, Butte MJ. MPEG1/Perforin-2 deficiency presenting with skin infections and considerations for interferon gamma therapy. Frontiers in Immunology, 2020, 11, 2852. PMID: 33224153. PMCID: PMC7670069
  12. Buchbinder D, Walter JE, Butte MJ, … , Collins CA. When Screening for Severe Combined Immunodeficiency (SCID) with T-cell Receptor Excision Circles is not SCID: A Case-based Review. Journal of Clinical Immunology, in press 2020.
  13. Zhang X, Kim T-H, Thauland TJ, Li H, Majedi FS, Ly C, Gu Z, Butte MJ, Rowat AC, Li S. Unraveling the Mechanobiology of Immune Cells. Current Opinion in Biotechnology. December 2020, vol 66, p. 236-245. Doi: 10.1016/j.copbio.2020.09.004. PMCID: PMC7524653
  14. Meitlis I, Allenspach EJ, … Butte MJ, … James RG. Multiplexed Functional Assessment of Genetic Variants in CARD11. The American Journal of Human Genetics. 2020 Dec 3;107(6):1029-43.
  15. Ahn TS, Han B, Krogstad P, Bun C, Kohn LA, Garcia-Lloret MI, Damoiseaux R, Butte MJ. Commercial immunoglobulin products contain cross-reactive but not neutralizing antibodies against SARS-CoV-2. Journal of Allergy and Clinical Immunology, 147 (3), 876-877, 2020.
  16. Meng KP, Majedi FS, Thauland TJ, Butte MJ. Tissue Mechanics Controls T-cell Activation and Metabolism. ACCEPTED, The Journal of Experimental Medicine, 2020.
  17. Tsai MS, Thauland TJ, Fitzwater S, Bun C, Garcia-Lloret MI, Krogstad P, Butte MJ. Refractory disseminated coccidioidomycosis disease successfully treated with IFN-gamma and dupilumab. ACCEPTED. New England Journal of Medicine.
  18. Deal CL, Thauland TJ, Stiehm ER, Garcia-Lloret MI, Butte MJ. Intact B-cell Signaling and Function With Host B-cells 47 years After Transplantation for X-SCID. ACCEPTED. Frontiers in Immunology.

2019

  1. Hu KH, Bruce MA, Liu J, and Butte MJ. Biochemical stimulation of immune cells and measurement of mechanical responses using atomic force microscopy. Current Protocols in Chemical Biology, 2019 Feb 1:e63.
  2. Amatuni GS, Currier RJ, Church JA, Bishop T, Grimbacher E, Nguyen AA, Agarwal-Hashmi R, Aznar CP, Butte MJ, Cowan MJ, Dorsey MJ, Dvorak CC, Kapoor N, Kohn DB, Markert ML, Moore TB, Naides SJ, Sciortino S, Feuchtbaum L, Koupaei RA, Puck JM. Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017. Pediatrics, 2019 Jan 25, pii: e20182300.
  3. Thauland TJ, Pellerin L, Ohgami RS, Bacchetta R, Butte MJ. Mechanism for increased follicular helper T cell development in activated PI3K delta syndrome. Frontiers in Immunology. 2019 Apr 12;10:753. PMID 31031754.
  4. Liu MM, Kohn LA, Roach GD, Garcia-Lloret MI, Butte MJ. Treatment of Systemic Mastocytosis in an Infant with Midostaurin. Journal of Allergy and Clinical Immunology in Practice. 2019 May 30. pii: S2213-2198(19)30489-1.
  5. Wang X, Balaji S, Steen EH, Li H, Rae MM, Blum AJ, Butte MJ, Bollyky PL, Keswani SG. Lymphocytes Attenuate Dermal Scarring by Regulating Inflammation, Neovascularization and Extracellular Matrix Remodeling. Advances in Wound Care. 2019 Nov 1;8(11): 527-537.
  6. Bosticardo M, Yamazaki Y, …, Butte MJ, …, Notarangelo LD. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. The American Journal of Human Genetics. 2019 Sep 5;105(3):549-561. doi: 10.1016/j.ajhg.2019.07.014. Epub 2019 Aug 22.
  7. Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Li S, Bouchard L-S, Butte MJ. Augmentation of T-cell activation by oscillatory forces and engineered antigen-presenting cells. Nano Letters. 2019 Oct 9;19(10): 6945-6954.
  8. Nguyen AN, Trompetto B, Tan XHM, Scott MB, Hu KH, Deeds E, Butte MJ, Chiou PY, Rowat, AC. Differential contributions of actin and myosin to the physical phenotypes and invasion of pancreatic cancer cells. Cell and Molecular Bioengineering, 2019 Oct 31;13(1):27-44.
  9. Lee H, Huang AY, Wang L-K, Yoon AJ, Renteria G, Eskin A, Signer RH, Dorrani N, Nieves-Rodrigues S, Wan J, Doune ED, Woods, JD, Dell’Angelica EC, Fogel BL, Martin MG, Butte MJ, Parker NH, Krakow D, Loo SK, Papp JC, Sinsheimer JS, Allard P, Shieh P, Palmer CG, Marinez-Agosto JA, Nelson SF. Integration of transcriptome analysis with whole genome sequencing analysis to augment diagnosis of rare Mendelian diseases in the Undiagnosed Diseases Network. Genetics in Medicine, 2019 Oct 14.
  10. Krogstad P, Johnson R, Garcia-Lloret MI, Heidari A, Butte MJ. Host-Pathogen Interactions in Coccidioidomycosis: Prognostic Clues and Opportunities for Novel Therapies. Clinical Therapeutics, 2019 Oct;41(10):1939-1954.e1.
  11. Thauland TJ, Khan HA, Butte MJ. The actin-capping protein alpha-adducin is required for T-cell costimulation. Frontiers of Immunology, 2019 Nov 20;10:2706. doi: 10.3389/fimmu.2019.02706. eCollection.
  12. Hu KH, Bruce MA, Liu J, and Butte MJ. Biochemical stimulation of immune cells and measurement of mechanical responses using atomic force microscopy. Current Protocols in Chemical Biololgy, 2019 Jun;11(2):e63. doi: 10.1002/cpch.63. Epub 2019 Feb 1.

2018

  1. Nagy N, de la Zerda A, Kaber G, Johnson PY, Hu KH, Kratochvil MJ, Yadava K, Zhao W, Cui Y, Navarro G, Annes JP, Wight TN, Heilshorn SC, Bollyky PL, Butte MJ. Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. The Journal of Biological Chemistry (JBC). 293.2 (2018): 567-578. pii: jbc.RA117.000148. PMID: 29183997.
  2. Majedi FS, Hasani‐Sadrabadi MM, Kidani Y, Thauland TJ, Moshaverinia A, Butte MJ, Bensinger SJ, Bouchard LS. Cytokine Secreting Microparticles Engineer the Fate and the Effector Functions of T‐Cells. Advanced Materials. 2018 Jan 8. [Epub ahead of print]
  3. Shashi V, Schoch K, Spillmann R, Cope H, Tan QK, Walley N, Pena L, McConkie-Rosell A, Jiang YH, Stong N, Need AC, Goldstein DB; Undiagnosed Diseases Network. A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative. Genet Med. 2018 Jun 15. PMID: 29907797.
  4. Lawless D, …, Butte MJ, … Savic S. Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency. 2018 Jun;141(6):2303-2306. PMID: 29477728.

2017

  1. Gebe JA, Ruppert S, Marshall P, Hill P, Falk BA, Sweere JM, Han H, Kaber G, Yadava K, Mikecz K, Ziegler SF, Balaji S, Keswani SG, de Jesus Perez VA, Butte MJ, Nadeau K, Altemeier WA, Fanger N, Bollyky PL. Modified Hyaluronan Promotes Allergen Specific Tolerance. American Journal of Respiratory Cell and Molecular Biology, 2017 Jan;56(1):109-120. PMID: 27598620.
  2. Thauland TJ, Hu KH, Bruce MA, Butte MJ. Cytoskeletal Adaptivity Regulates T Cell Receptor Signaling. Science Signaling. 2017 Mar 7;10(469). PMID: 28270556.
    • This paper was chosen for the cover image.
  3. Lee YN, Frugoni F, …, Butte MJ, …, Walter JE, Notarangelo LD. Tailoring the immune repertoire with RAGs: Restriction of IGH and TRB repertoire correlates with clinical severity of RAG deficiency. Science Immunology. 2016 Dec 16;1(6). pii: eaah6109. Epub 2016 Dec 16. PMID: 28783691.
  4. Balaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG. Interleukin-10 Mediated Regenerative Postnatal Tissue Repair is Dependent on Regulation of Hyaluronan Metabolism via Fibroblast-specific STAT3 Signaling. FASEB J, 2017 Mar;31(3):868-881. PMID: 27903619.
  5. Choi J, Fernandez R, Maecker HT, Butte MJ. Systems Biology Approach to Uncover Signaling Defects in Primary Immunodeficiency Diseases. Journal of Allergy and Clinical Immunology, 2017 Apr 12. pii: S0091-6749(17)30586-9. PMID: 28412396
    • This paper was highlighted in Science Immunology: “Beyond spell checking: Adding function to precision medicine” by Sarah Henrickson (Science Immunology 2.11 (2017): eaan5141.)
  6. Kulkarni S, Fu Y-Y, Tang S-C, Leser J, Liu L, Li Q, Li C, Enikolopov G, Becker L, Butte MJ, Song J, Southard-Smith M, Kapur RP, Micci M-A, Pasricha PJ. The adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. PNAS, 2017 Apr 18. pii: 201619406. PMID: 28420791.
  7. Nyberg KD, Hu KH, Kleinman S, Khismatullin DB, Butte MJ, Rowat AC. Quantitative Deformability Cytometry: Rapid, Calibrated Measurements of Cell Mechanical Properties. Biophysical Journal. 2017 Oct 3;113(7):1574-1584. PMID: 28978449.

2016

  1. Kuipers HF, Rieck M, Gurevich I, Nagy N, Butte MJ, Negrin RS, Wight TN, Steinman L, Bollyky PL. Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization. PNAS. 2016 Feb 2;113(5):1339-44. Epub 2016 Jan 19. PMID: 26787861.
  2. Wang A*, Vijayraghavan K*, Solgaard O, Butte MJ. Fast Stiffness Mapping of Cells Using High-Bandwidth Atomic Force Microscopy. ACS Nano. 2016 Jan 26;10(1):257-64. Epub 2015 Dec 15. PMID: 26554581.
  3. Rael E, Rakszawski L, Koller K, Bayerl M, Butte MJ, Zheng H. Treatment with rituximab and brentuximab vedotin in a patient of common variable immune deficiency-associated classic Hodgkin lymphoma. Biomarker Research. 2016, In press.
  4. Han LH, Conrad B, Chung MT, Deveza L, Jiang X, Wang A, Butte MJ, Longaker MT, Wan D, Yang F. Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model. J Biomed Mater Res A. 2016 Mar 17.
  5. Nam S, Hu KH, Butte MJ, Chaudhuri O. Strain-enhanced stress relaxation regulates nonlinear elasticity in biopolymer gels. PNAS. 2016, In press.
  6. Hu KH and Butte MJ. T cell activation requires force generation. J. Cell Biology. 2016, In press.

2015

  1. Mathieu A-L, ..., Butte MJ, ..., Belot A. PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity. In press (2015), J. Allergy and Clinical Immunology.
  2. Matthews AGW, Briggs CE, Yamanaka K, Small TN, Mooster JL, Bonilla FA, Oettinger MA, Butte MJ. Compound Heterozygous Mutation of Rag1 leading to Omenn Syndrome. PLoS ONE. 10(4): e0121489.
  3. Kanada M, Bachmann MH, Hardy JW, Bronsart L, Wang A, Frimannson DO, Sylvester MD, Schmidt TL, Kaspar RL, Butte MJ, Matin AC, Contag CH. Differential fates of biomolecules delivered to target cells via extracellular vesicles. PNAS. 112.12 (2015): E1433-E1442.
  4. Walter J, ..., Butte MJ, ... Notarangelo LD. Broad Spectrum Antibodies to Self-Antigens and Cytokines in RAG Deficiency. In press (2015), J. Clinical Investigation.
  5. Wei K*, Serpooshan V*, Metzler SE, Zhao M, Shah PB, Kim PJ, Savtchenko A, Wang A, Diez-Cunado M, Cai W, Wei K, Spiering S, Zhu W, Butte MJ, Yang P, Bernstein D, Mercola M, Ruiz-Lozano P. Engineered Epicardium Activates Cardiac Regeneration. In press, Nature (2015).

2014

  1. Serpooshan V, Zhao M, Metzler S, Weo K, Shah, PB, Wang, A, Mahmoudi M, Malkovskiy AV, Rajadas J, Butte MJ, Bernstein D, Ruiz-Lozano, P (2014). Use of bio-mimmetic 3D technology in therapeutics for heart disease. Bioengineered, 5(3), 0-1 (2014). PMID: 24637710.
  2. Hu KK, Bruce MA, Butte MJ. Spatiotemporally and mechanically controlled triggering of mast cells using atomic force microscopy. Immunol Res. 58(2-3):211-7 (May 2014). PMID: 24777418.
  3. Wang A, Butte MJ. Customized atomic force microscopy probe by focused-ion-beam-assisted tip transfer. Applied Physics Letters, 105(5):053101 (Aug 2014). PMID: 25161320.
  4. Burridge P, Metzler S, Nakayama K, Abilez O, Simmons C, Bruce M, Matsuura Y, Kim P, Wu J, Butte MJ, Huang N, Yang P. Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes. American Journal of Translational Research, 6(6):724-735 (Nov 2014).

2013

  1. Vijayraghavan K, Gellineau AA, Wang A, Butte MJ, Melosh NA, Solgaard O. Modeling, design, and fabrication of a high bandwidth AFM probe for imaging in air and water. J. Micromechanical Systems. 22(3):603-612. Jun 2013.
  2. Bruce MA, Butte MJ. Real-time GPU-based 3D Deconvolution. Optics Express. Vol. 21, Issue 4, pp. 4766-4773, Feb 2013. PMID 23482010.
  3. Vijayraghavan K, Wang A, Solgaard O, Butte MJ, Melosh NA. Measurement of Elastic Properties in Fluid Using High Bandwidth AFM Probes. Applied Physics Letters, 102, 103111 (2013).
  4. Sun W, Araci Z, Inayathullah M, Manickam S, Zhang X, Bruce MA, Marinkovich MP, Lane AT, Milla C, Rajadas J, Butte MJ. Polyvinylpyrrolidone microneedles enable delivery of intact proteins for diagnostic and therapeutic applications. Acta Biomaterialia, 9 (8), 7767-7774 (2013). PMID: 23648574.
  5. Serpooshan V, Wei K, Zhao M, Metzler SA, Shah PB, Wang A, Mahmoudi M, Butte MJ, Bernstein D, Ruiz-Lozano P. Bioengineered Acellular Collagen Patch Attenuates Cardiac Remodeling and Improves Ventricular Function post Myocardial Infarction. Biomaterials. 34.36: 9048-9055 (2013). PMID: 23992980.

2009-2012

  1. LeBlanc J, Mueller AJ, Prinz A, Butte MJ. Optical Planar Waveguide for Cell Counting. Applied Physics Letters, 2012 Jan 23;100(4):43701-437015. PMID 22331960. Garcia D, Ghansah I, LeBlanc J, Butte MJ. Counting cells with a low-cost integrated microfluidics-waveguide sensor. Biomicrofluidics, 2012 Mar;6(1):14115-141154. Epub 2012 Mar 7. PMID 22454696.
  2. Ge X, Wang IE, Toma I, Sebastiano V, Liu J, Butte MJ, Reijo Pera R, Yang PC. Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells. Stem Cells and Development. 2012 Oct 10;21(15):2798-808. doi: 10.1089/scd.2011.0435. Epub 2012 Jun 11. PMID 22530853.
  3. Sun N, Yazawa M, Navarrete EG, Sanchez-Freire V, Hu S, Wang L, Han L, Lee A, Abilez OJ, Pavlovic A, Liu J, Hajjar RJ, Dolmetsch RE, Butte MJ, Ashley EA, Longaker MT, Robbins RC, Wu JC. Patient-Specific Induced Pluripotent Stem Cell as A Model for Familial Dilated Cardiomyopathy. Science Translational Medicine, 2012 Apr 18;4(130):130ra47. PMID 22517884.
  4. Liu J, Sun N, Bruce MA, Wu JC, Butte MJ. Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes. PLoS ONE, 7(5):e37559. Epub 2012 May 18. PMID 22624048.
  5. Wang IN, Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells. PLoS ONE, 2012; 7(6): e38328. Epub 2012 Jun 1. PMID 22675543.
  6. Butte MJ*, Lee SJ*, Jesneck J, Keir ME, Haining WN, Sharpe AH. Sharpe CD28 costimulation regulates genome-wide effects on alternative splicing. PLoS ONE, 2012;7(6):e40032. Epub 2012 Jun 29. *co-first author. PMID 22768209
  7. Liu J, Butte MJ. Single Molecule Labeling of an AFM Cantilever Tip. Applied Physics Letters, 101, 163705 (Dec 2012). PMID 23152642.

2004-2009 (Manish Immunology Fellowship and Postdoc with George Whitesides and Arlene Sharpe at Harvard)

  1. Mack ET, Snyder PW; Perez-Castillejos R, Bilgicer B, Moustakas D, Butte MJ, Whitesides GM. Dependence of Avidity on Linker Length for a Bivalent Ligand-Bivalent Receptor Model System. J. American Chemical Society, 2012 Jan 11;134(1):333-45. Epub 2011 Dec 21. PMID 22088143.
  2. Butte MJ, Pena-Cruz V, Kim MJ, Freeman GJ, Sharpe AH. Interaction of Human PD-L1 and B7-1. Molecular Immunology, 2008 Aug; 45(13):3567-72. PMID 18585785. Reches M, Mirica KA, Dasgupta R, Dickey MD, Butte MJ, Whitesides GM. Thread as a matrix for biomedical assays. ACS Appl Mater Interfaces. 2010 Jun;2(6):1722-8. PMID: 20496913.
  3. McGuigan AP, Bruzewicz DA, Glavan A., Butte MJ, Whitesides GM. Cell encapsulation in sub-mm sized gel modules using replica molding. PLoS ONE. 2008 May 21;3(5):e2258. PMID 18493609.
  4. Martinez AW, Phillips ST, Butte MJ, Whitesides GM. Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angew Chem Int Ed Engl. 2007;46(8):1318-20. PMID 17211899.
  5. Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007;27(1):111-22. PMID 17629517.
  6. Grabie N, Gotsman I, DaCosta R, Pang H, Stavrakis G, Butte MJ, Keir ME, Freeman GJ, Sharpe AH, Lichtman AH. Endothelial programmed death-1 ligand 1 (PD-L1) regulates CD8+ T-cell mediated injury in the heart. Circulation. 2007;116(18):2062-71. PMID 17938288.
  7. Butte MJ*, Haines C*, Bonilla FA, Puck J. IL-7 receptor deficient SCID with a unique intronic mutation and post-transplant autoimmunity due to chronic GVHD. Clinical Immunology. 2007;125(2):159-64. *co-first author. PMID 17827065.
  8. Kobayashi N, Karisola P, Peña-Cruz V, Dorfman DM, Jinushi M, Umetsu SE, Butte MJ, Nagumo H, Chernova I, Zhu B, Sharpe AH, Ito S, Dranoff G, Kaplan GG, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells. Immunity. 2007;27(6):927-40. PMID 18082433.
  9. Butte MJ, Dodson B, Dioun A. Pentobarbital desensitization in a 3 month old child. Allergy and Asthma Proceedings, 2004 Jul-Aug; 25(4): 225-7. PMID 15510580.

Pre-2000 (Manish in PhD program in Fletterick Lab at UCSF)

  1. Butte MJ. Neurotrophic factor structures reveal clues to evolution, binding, specificity, and receptor activation (invited review article). Cell Mol Life Sci., 2001 Jul; 58(8): 1003-13. PMID 11529493.
  2. Butte MJ, Hwang PK, Mobley WC, Fletterick RJ. Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry, 1998 Dec 1; 37(48): 16846-52. PMID 9836577.
  3. Read D, Butte MJ. Dernburg AF, Frasch M, Kornberg TB. Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins. Nucleic Acids Res., 2000 Oct 15; 28(20): 3864-70. PMID 11024164.

Pre-1995 (Manish in medical school at Brown)

  1. Bertram R, Butte MJ, Kiemel T, Sherman A. Topological and phenomenological classification of bursting oscillations. Bulletin Math. Biol., 1995 May; 57(3): 413-39. PMID 7728115.
  2. Butte MJ, Nguyen BX, Hutchison TJ, Wiggins JW, Ziegler JW. Pediatric myocardial infarction after racemic epinephrine administration. Pediatrics, 1999 Jul; 104(1): e9. PMID 10390295.